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1

Classroom Verbal Behavior of Highly Effective Teachers

Jon F. Nussbaum, Sherry J. Holladay and Mark E. Comadena

Journal:

Journal of Thought

Année:

1987

Langue:

english

Fichier:

PDF, 896 KB

english, 1987

2

Structure – activity relationships of nicotinic acetylcholine receptor agonists as potential treatments for dementia

Mark W. Holladay, Suzanne A. Lebold, Nan-Horng Lin

Journal:

Drug Development Research

Année:

1995

Langue:

english

Fichier:

PDF, 2.28 MB

english, 1995

3

Synthesis of hydroxyethylene and ketomethylene dipeptide isosteres

Mark W. Holladay, Daniel H. Rich

Journal:

Tetrahedron Letters

Année:

1983

Langue:

english

Fichier:

PDF, 210 KB

english, 1983

4

Structure–Activity studies for a novel series of tricyclic dihydropyrimidines as KATP channel openers (KCOs)

Irene Drizin, Mark W. Holladay, Lin Yi, Henry Q. Zhang, Sujatha Gopalakrishnan, Murali Gopalakrishnan, Kristi L. Whiteaker, Steven A. Buckner, James P. Sullivan, William A. Carroll

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2002

Langue:

english

Fichier:

PDF, 121 KB

english, 2002

5

Conformationally constrained amino acids. Synthesis and optical resolution of 3-substituted proline derivatives

Chung, John Y. L., Wasicak, James T., Arnold, William A., May, Catherine S., Nadzan, Alex M., Holladay, Mark W.

Journal:

Journal of Organic Chemistry

Année:

1990

Langue:

english

Fichier:

PDF, 879 KB

english, 1990

6

trans-3-n-propyl-L-proline is a highly favorable, conformationally restricted replacement for methionine in the C-terminal tetrapeptide of cholecystokinin. Stereoselective synthesis of 3-allyl- and 3-n-propyl-L-proline derivatives from 4-hydroxy-L-proline

Holladay, Mark W., Lin, Chun Wel, May, Catherine S., Garvey, David S., Witte, David G., Miller, Thomas R., Wolfram, Caroline A. W., Nadzan, Alex M.

Journal:

Journal of Medicinal Chemistry

Année:

1991

Langue:

english

Fichier:

PDF, 412 KB

english, 1991

7

Kinetic and thermodynamic investigation of hydrogen release from ethane 1,2-di-amineborane

Neiner, Doinita, Karkamkar, Abhi, Bowden, Mark, Joon Choi, Young, Luedtke, Avery, Holladay, Jamie, Fisher, Allison, Szymczak, Nathaniel, Autrey, Tom

Journal:

Energy & Environmental Science

Année:

2011

Langue:

english

Fichier:

PDF, 410 KB

english, 2011

8

Length minimization for Poisson confidence procedures

Schilling, Mark, Holladay, Bret

Journal:

Communication in Statistics- Theory and Methods

Année:

2016

Langue:

english

Fichier:

PDF, 897 KB

english, 2016

9

[American Institute of Aeronautics and Astronautics 31st AIAA Aerodynamic Measurement Technology and Ground Testing Conference - Dallas, TX ()] 31st AIAA Aerodynamic Measurement Technology and Ground Testing Conference - NASA Data Acquisition System Software Development for Rocket Propulsion Test Facilities

Hebert, Phillip W., Davis, Dawn M., Turowski, Mark P., Holladay, Wendy T., Marshall, Peggi L., Duncan, Michael E., Morris, Jon A., Franzi, Richard W.

Langue:

english

Fichier:

PDF, 1.67 MB

english

10

ABT-089 [3-(2(S)-pyrrolidinylmethoxy)-2-methyl-pyridine]: An orally effective cholinergic channel modulator with potential once-a-day dosing and cardiovascular safety

Stephen P. Arneric, Jeffrey E. Campbell, Sherry Carroll, Jerome F. Daanen, Mark W. Holladay, P. Johnson, Nan-Horng Lin, Kennan C. Marsh, Bud Peterson, Yihong Qui, Ellen M. Roberts, A. David Rodrigues,

Journal:

Drug Development Research

Année:

1997

Langue:

english

Fichier:

PDF, 294 KB

english, 1997

11

ChemInform Abstract: Solid-Phase Heterocyclic Chemistry

Viktor Krchnak, Mark W. Holladay

Journal:

Année:

2002

Fichier:

PDF, 24 KB

2002

12

Bioaccumulation of 2,4,6-trinitrotoluene and polychlorinated biphenyls through two routes of exposure in a terrestrial amphibian: Is the dermal route significant?

Mark S. Johnson, Laura S. Franke, Robyn B. Lee, Steven D. Holladay

Journal:

Environmental Toxicology and Chemistry

Année:

1999

Langue:

english

Fichier:

PDF, 88 KB

english, 1999

13

Influence of dietary 2,4,6-trinitrotoluene exposure in the northern bobwhite (Colinus virginianus)

Robert M. Gogal Jr., Mark S. Johnson, Calvert T. Larsen, Mary R. Prater, Robert B. Duncan, Daniel L. Ward, Steven D. Holladay

Journal:

Environmental Toxicology and Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 122 KB

english, 2002

14

2-(Aryloxymethyl) azacyclic analogues as novel nicotinic acetylcholine receptor (nAChR) ligands

Richard L. Elliott, Hana Kopecka, David E. Gunn, Nan-Horng Lin, David S. Garvey, Keith B. Ryther, Mark W. Holladay, David J. Anderson, Jeffrey E. Campbell, James P. Sullivan, Michael J. Buckley, Karen

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

1996

Langue:

english

Fichier:

PDF, 346 KB

english, 1996

15

Efficient asymmetric synthesis of ABT-594; a potent, orally effective analgesic

John K. Lynch, Mark W. Holladay, Keith B. Ryther, Hao Bai, Chi-Nung Hsiao, Howard E. Morton, Daniel A. Dickman, William Arnold, Steven A. King

Journal:

Tetrahedron: Asymmetry

Année:

1998

Langue:

english

Fichier:

PDF, 85 KB

english, 1998

16

Synthesis and structure–activity relationships of 5-substituted pyridine analogues of 3-[2-((S)-pyrrolidinyl)methoxy]pyridine, A-84543: A potent nicotinic receptor ligand

Nan-Horng Lin, Yihong Li, Yun He, Mark W Holladay, Theresa Kuntzweiler, David J Anderson, Jeffrey E Campbell, Stephen P Arneric

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2001

Langue:

english

Fichier:

PDF, 105 KB

english, 2001

17

Novel 2-(2′-furo[3,2-b]pyridinyl) pyrrolidines: potent neuronal nicotinic acetylcholine receptor ligands

Richard L. Elliott, Keith B. Ryther, David J. Anderson, Marietta Piattoni-Kaplan, Theresa A. Kuntzweiler, Diana Donnelly-Roberts, Stephen P. Arneric, Mark W. Holladay

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

1997

Langue:

english

Fichier:

PDF, 326 KB

english, 1997

18

Structure-activity studies related to ABT-594, a potent nonopioid analgesic agent: Effect of pyridine and azetidine ring substitutions on nicotinic acetylcholine receptor binding affinity and analgesic activity in mice

Mark W. Holladay, Hao Bai, Yihong Li, Nan-Horng Lin, Jerome F. Daanen, Keith B. Ryther, James T. Wasicak, John F. Kincaid, Yun He, Anne-Marie Hettinger, Peggy Huang, David J. Anderson, Anthony W. Bann

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

1998

Langue:

english

Fichier:

PDF, 327 KB

english, 1998

19

Amino acid-derived piperidides as novel CCKB ligands with anxiolytic-like properties

Mark W. Holladay, Michael J. Bennett, Hao Bai, Jeffrey W. Ralston, James F. Kerwin Jr., Michael Stashko, Thomas R. Miller, Alyssa B. O'Neill, Alex M. Nadzan, Jorge Brioni, Chun Wel Lin

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

1995

Langue:

english

Fichier:

PDF, 254 KB

english, 1995

20

Double bond isosteres of the peptide bond: Synthesis and biological activity of cholecystokinin (CCK) C-terminal hexapeptide analogs

Youe-Kong Shue, Michael D. Tufano, George M. Carrera Jr, Hana Kopecka, Sharon L. Kuyper, Mark W. Holladay, Chun Wel Lin, David G. Witte, Thomas R. Miller, Mike Stashko, Alex M. Nadzan

Journal:

Bioorganic & Medicinal Chemistry

Année:

1993

Langue:

english

Fichier:

PDF, 1.44 MB

english, 1993

21

Dietary oral exposure to 1,3,5-trinitro-1,3,5-triazine in the northern bobwhite (Colinus virginianus)

Robert M. Gogal Jr., Mark S. Johnson, Calvert T. Larsen, Mary R. Prater, Robert B. Duncan, Daniel L. Ward, Robyn B. Lee, Christopher J. Salice, Bernard Jortner, Steven D. Holladay

Journal:

Environmental Toxicology and Chemistry

Année:

2003

Langue:

english

Fichier:

PDF, 86 KB

english, 2003

22

Ligands for Brain Cholinergic Channel Receptors: Synthesis and in Vitro Characterization of Novel Isoxazoles and Isothiazoles as Bioisosteric Replacements for the Pyridine Ring in Nicotine

Garvey, David S., Wasicak, James T., Elliott, Richard L., Lebold, Suzanne, Hettinger, Ann-Marie, Carrera, George M., Lin, Nan-Horng, He, Yun, Holladay, Mark W.

Journal:

Journal of Medicinal Chemistry

Année:

1994

Langue:

english

Fichier:

PDF, 1.29 MB

english, 1994

23

Neuronal nicotinic receptors: A perspective on two decades of drug discovery research

Stephen P. Arneric, Mark Holladay, Michael Williams

Journal:

Biochemical Pharmacology

Année:

2007

Langue:

english

Fichier:

PDF, 511 KB

english, 2007

24

Novel series of pyrrolotriazine analogs as highly potent pan-Aurora kinase inhibitors

Sunny Abraham, Michael J. Hadd, Lan Tran, Troy Vickers, Janice Sindac, Zdravko V. Milanov, Mark W. Holladay, Shripad S. Bhagwat, Helen Hua, Julia M. Ford Pulido, Merryl D. Cramer, Dana Gitnick, Joyce

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2011

Langue:

english

Fichier:

PDF, 2.20 MB

english, 2011

25

4-Quinazolinyloxy-diaryl ureas as novel BRAFV600E inhibitors

Mark W. Holladay, Brian T. Campbell, Martin W. Rowbottom, Qi Chao, Kelly G. Sprankle, Andiliy G. Lai, Sunny Abraham, Eduardo Setti, Raffaella Faraoni, Lan Tran, Robert C. Armstrong, Ruwanthi N. Gunawa

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2011

Langue:

english

Fichier:

PDF, 666 KB

english, 2011

26

The role of neuronal nicotinic acetylcholine receptors in antinociception: Effects of ABT-594

Michael W. Decker, Peter Curzon, Mark W. Holladay, Arthur L. Nikkel, R. Scott Bitner, Anthony W. Bannon, Diana L. Donnelly-Roberts, Pamela S. Puttfarcken, Theresa A. Kuntzweiler, Clark A. Briggs, Mich

Journal:

Journal of Physiology-Paris

Année:

1998

Langue:

english

Fichier:

PDF, 338 KB

english, 1998

27

Neuronal nicotinic ACh receptor modulators

Mark W Holladay

Journal:

Drug Discovery Today

Année:

1998

Langue:

english

Fichier:

PDF, 102 KB

english, 1998

28

Fate and the Biochemical Effects of 2,4,6-Trinitrotoluene Exposure to Tiger Salamanders (Ambystoma tigrinum)

Mark S. Johnson, Jayant K. Vodela, Gunda Reddy, Steven D. Holladay

Journal:

Ecotoxicology and Environmental Safety

Année:

2000

Langue:

english

Fichier:

PDF, 138 KB

english, 2000

29

Identification of oxygen nucleophiles in tetrahedral intermediates: 2H and 18O induced isotope shifts in 13C NMR spectra of pepsin-bound peptide ketone pseudosubstrates

Paul G. Schmidt, Mark W. Holladay, Francesco G. Salituro, Daniel H. Rich

Journal:

Biochemical and Biophysical Research Communications

Année:

1985

Langue:

english

Fichier:

PDF, 337 KB

english, 1985

30

Novel Isoxazoles which Interact with Brain Cholinergic Channel Receptors Have Intrinsic Cognitive Enhancing and Anxiolytic Activities

Garvey, David S., Wasicak, James T., Decker, Michael W., Brioni, Jorge D., Buckley, Michael J., Sullivan, James P., Carrera, George M., Holladay, Mark W., Arneric, Stephen P., Williams, Michael

Journal:

Journal of Medicinal Chemistry

Année:

1994

Langue:

english

Fichier:

PDF, 609 KB

english, 1994

31

Convenient Preparation of O -Linked Polymer-Bound N -Substituted Hydroxylamines, Intermediates for Synthesis of N -Substituted Hydroxamic Acids

Robinson, Dale E., Holladay, Mark W.

Journal:

Organic Letters

Année:

2000

Langue:

english

Fichier:

PDF, 75 KB

english, 2000

32

Genetic testing for Alpha1-antitrypsin deficiency

Strange, Charlie, Dickson, Ryan, Carter, Cindy, Carpenter, Matthew J, Holladay, Brian, Lundquist, Ryan, Brantly, Mark L

Journal:

Genetics in Medicine

Année:

2004

Langue:

english

Fichier:

PDF, 325 KB

english, 2004

33

Antinociceptive effects of the novel neuronal nicotinic acetylcholine receptor agonist, ABT-594, in mice

Michael W Decker, Anthony W Bannon, Michael J Buckley, David J.B Kim, Mark W Holladay, Keith B Ryther, Nan-Horng Lin, James T Wasicak, Michael Williams, Stephen P Arneric

Journal:

European Journal of Pharmacology

Année:

1998

Langue:

english

Fichier:

PDF, 189 KB

english, 1998

34

Solid Phase Heterocyclic Chemistry

Krchňák, Viktor, Holladay, Mark W.

Journal:

Chemical Reviews

Année:

2002

Langue:

english

Fichier:

PDF, 436 KB

english, 2002

35

Discovery of Highly Potent and Selective Pan-Aurora Kinase Inhibitors with Enhanced in Vivo Antitumor Therapeutic Index

Liu, Gang, Abraham, Sunny, Tran, Lan, Vickers, Troy D., Xu, Shimin, Hadd, Michael J., Quiambao, Sheena, Holladay, Mark W., Hua, Helen, Ford Pulido, Julia M., Gunawardane, Ruwanthi N., Davis, Mindy I.,

Journal:

Journal of Medicinal Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 451 KB

english, 2012

36

Identification and Initial Structure−Activity Relationships of ( R )-5-(2-Azetidinylmethoxy)-2-chloropyridine (ABT-594), a Potent, Orally Active, Non-Opiate Analgesic Agent Acting via Neuronal Nicotinic Acetylcholine Receptors

Holladay, Mark W., Wasicak, James T., Lin, Nan-Horng, He, Yun, Ryther, Keith B., Bannon, Anthony W., Buckley, Michael J., Kim, David J. B., Decker, Michael W., Anderson, David J., Campbell, Jeffrey E.

Journal:

Journal of Medicinal Chemistry

Année:

1998

Langue:

english

Fichier:

PDF, 91 KB

english, 1998

37

Synthesis of .alpha.-benzyl .gamma.-lactam, .alpha.-benzyl .delta.-lactam, and .alpha.-benzylproline derivatives as conformationally restricted analogs of phenylalaninamide

Holladay, Mark W., Nadzan, Alex M.

Journal:

Journal of Organic Chemistry

Année:

1991

Langue:

english

Fichier:

PDF, 866 KB

english, 1991

38

Synthetic and enzyme inhibition studies of pepstatin analogs containing hydroxyethylene and ketomethylene dipeptide isosteres

Holladay, Mark W., Salituro, Francesco G., Rich, Daniel H.

Journal:

Journal of Medicinal Chemistry

Année:

1987

Langue:

english

Fichier:

PDF, 1.47 MB

english, 1987

39

Neuronal Nicotinic Acetylcholine Receptors as Targets for Drug Discovery †

Holladay, Mark W., Dart, Michael J., Lynch, John K.

Journal:

Journal of Medicinal Chemistry

Année:

1997

Langue:

english

Fichier:

PDF, 639 KB

english, 1997

40

Pterygia as cause of post-cataract with-the-rule astigmatism

Holladay, Jack T., Lewis, John W., Allison, Mark E., Ruiz, Richard S.

Journal:

American Intra-Ocular Implant Society Journal

Année:

1985

Langue:

english

Fichier:

PDF, 900 KB

english, 1985

41

Factors associated with advanced liver disease in adults with alpha1-antitrypsin deficiency

Bowlus, Christopher L., Willner, Ira, Zern, Mark A., Reuben, Adrian, Chen, Philip, Holladay, Brian, Xie, Lianqi, Woolson, Robert F., Strange, Charlie

Journal:

Clinical Gastroenterology and Hepatology

Année:

2005

Langue:

english

Fichier:

PDF, 148 KB

english, 2005

42

Corneal topography in Ehlers-Danlos syndrome

McDermott, Mark L., Holladay, Jack, Liu, David, Puklin, James E., Shin, Dong H., Cowden, John W.

Journal:

Journal of Cataract & Refractive Surgery

Année:

1998

Langue:

english

Fichier:

PDF, 1.30 MB

english, 1998

43

Biologically oriented organic sulfur chemistry. 15. Organic disulfides and related substances. 41. Inhibition of the fungal pathogen Histoplasma capsulatum by some organic disulfides

Field, Lamar, Grimaldi, John A. R., Hanley, Wayne S., Holladay, Mark W., Ravichandran, Ramanathan, Schaad, Lawrence J., Tate, C. Emory

Journal:

Journal of Medicinal Chemistry

Année:

1977

Langue:

english

Fichier:

PDF, 896 KB

english, 1977

44

Stereospecific total syntheses of the natural antitumor agent, (.alpha.S, 5S)-.alpha.-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid, and its unnatural C-5 epimer

Silverman, Richard B., Holladay, Mark W.

Journal:

Journal of the American Chemical Society

Année:

1981

Langue:

english

Fichier:

PDF, 298 KB

english, 1981

45

Tetrapeptide CCK-A Agonists: Effect of Backbone N-Methylations on in vitro and in vivo CCK Activity

Holladay, Mark W., Kopecka, Hana, Miller, Thomas R., Bednarz, Lisa, Nikkel, A. L., Bianchi, Bruce R., Witte, David G., Shiosaki, Kazumi, Lin, Chun Wel

Journal:

Journal of Medicinal Chemistry

Année:

1994

Langue:

english

Fichier:

PDF, 934 KB

english, 1994

46

Lycaconitine Revisited: Partial Synthesis and Neuronal Nicotinic Acetylcholine Receptor Affinities

Jacyno, John M., Harwood, John S., Lin, Nan-Horng, Campbell, Jeffrey E., Sullivan, James P., Holladay, Mark W.

Journal:

Journal of Natural Products

Année:

1996

Langue:

english

Fichier:

PDF, 129 KB

english, 1996

47

Goldmann Applanation Tonometry in Patients with Regular Corneal Astigmatism

Holladay, Jack T., Allison, Mark E., Prager, Thomas C.

Journal:

American Journal of Ophthalmology

Année:

1983

Langue:

english

Fichier:

PDF, 449 KB

english, 1983

48

Synthesis and biological activity of CCK heptapeptide analogs. Effects of conformational constraints and standard modifications on receptor subtype selectivity, functional activity in vitro, and appetite suppression in vivo

Holladay, Mark W., Bennett, Michael J., Tufano, Michael D., Lin, C. W., Asin, Karen E., Witte, David G., Miller, Thomas R., Bianchi, Bruce R., Nikkel, A. L.

Journal:

Journal of Medicinal Chemistry

Année:

1992

Langue:

english

Fichier:

PDF, 1.47 MB

english, 1992

49

Discovery of AC710, a Globally Selective Inhibitor of Platelet-Derived Growth Factor Receptor-Family Kinases

Liu, Gang, Campbell, Brian T., Holladay, Mark W., Ford Pulido, Julia M., Hua, Helen, Gitnick, Dana, Gardner, Michael F., James, Joyce, Breider, Mike A., Brigham, Daniel, Belli, Barbara, Armstrong, Rob

Journal:

ACS Medicinal Chemistry Letters

Année:

2012

Langue:

english

Fichier:

PDF, 322 KB

english, 2012

50

[Advances in Medicinal Chemistry] Volume 5 || Discovery of ABT-594 and related neuronal nicotinic acetylcholine receptor modulators as analgesic agents

Holladay, Mark W.

Année:

2000

Langue:

english

Fichier:

PDF, 1.34 MB

english, 2000